兼任老師

洪佩詩 助理教授

洪佩詩 助理教授

詳細介紹
電子郵件:g39017005@gmail.com 
聯絡電話:(03)9325192分機3218
最高學歷:國立陽明大學口腔生物研究所博士 
專長:口腫瘤生物學、分子生物學
 

。學經歷

2012/07-迄今            國立陽明大學附設醫院 研究員副院長
2007/12-2012/07     國立陽明大學 口腔生物研究所 博士後研究員

。榮譽成就

2008    國立陽明大學「研究生優秀論文獎助」甲等論文獎助
2008    中華民國第23屆生物醫學聯合學術年會「優良看板論文壁報獎」
2006    榮獲國立陽明大學94學年度學術論文研討會榮獲「臨床醫學與公共衛生研究組」優等獎

。實驗室研究方向

        The expression and functions of miRNAs in oral, gastric and breast cancer.

                         

。研究計畫  

計畫執行年限 計畫名稱
2015/01-2014/12 National Yang-Ming University Hospital, The miRNAs which could contributes to paclitaxel resistance of breast cancer cells, RD2015-033.
2014/01~2014/12 National Yang-Ming University Hospital, The regulation mechanisms of stomatin in breast cancer, RD2014-033.

。代表著作

  1. Liu CJ, Tsai MM, Hung PS, Kao-SY, Liu TY, Wu KJ, Chiou SH, Lin SC*, Chang KW*. miRNA-31 ablates expression of the HIF regulatory factor FIH to activate the HIF pathway in head and neck carcinoma. Cancer Research 2010; 15;70(4):1635-1644
  2. Lin SC, Liu CJ, Lin JA, Chiang WF, Hung PS, Chang KW*. miRNA-24 up-regulation in oral carcinoma: positive association from clinical and in vitro analysis. Oral Oncology 2010; 46(3):204-208.
  3. Hung PS#, Chen FC#, Kuang SH, Kao SY, Lin SC*, Chang KW*. miRNA-146a induces differentiation of periodontal ligament cells. Journal of Dental Research 2010; 89(3):252-257.
  4. Chang KW#, Hung PS#, Lin IY, Hou CP, Chen LK, Tsai YM, Lin SC*. Curcumin upregulates insulin-like growth factor binding protein-5 (IGFBP-5) and C/EBPα during oral cancer suppression. International Journal of Cancer 2010; 127(1):9-20.
  5. Yang CC#, Hung PS#, Wang PW, Liu CJ, Chu TH, Cheng HW, Lin SC*.  miRNA-181 as a putative biomarker for lymph-node metastasis of oral squamous cell carcinoma. Journal of Oral Pathology & Medicine 2011; 40: 397-404.
  6. Chiang WF#, Hung PS#, Liu SY, Yuan TC, Chang KW, Chen YP, Liu YC, Lin SC*. Increase of ZASC1 gene copy number in recurrent oral carcinoma. Oral Diseases 2011; 17:53-59.
  7. Lo SS*, Hung PS, Chen JH, Tu HF, Fang WL, Chen CY, Chen WT, Gong NR, Wu CW. Overexpression of miRNA-370 and downregulation of its novel target TGFβ-RII contribute to the progression of gastric carcinoma. Oncogene 2102; 31(2):226-237.
  8. Hung PS#, Chang KW#, Kao SY, Chu TH, Liu CJ, Lin SC*. Association between the re2910164 polymorphism in pre-miRNA-146a and oral carcinoma progression. Oral Oncology 2012; 48(5):404-408.
  9. Wang MC#, Hung PS#, Tu HF, Shih WY, Li WC, Chang KW. Lipopolysaccharide induces the migration of human dental pulp cells by up-regulating miRNA-146a. Journal of Endodontics 2012;38(12):1598-1603.
  10. Hung PS#, Liu CJ#, Chou CS, Kao SY, Yang CC, Chang KW, Chiu TH, Lin SC*. miR-146a enhances the oncogenicity of oral carcinoma by concomitant targeting of the IRAK1, TRAF6 and NUMB genes. PLOS One 2013; 26;8(11):e79926.
  11. Hung PS#, Tu HF#, Kao SY, Yang CC, Liu CJ, Huang TY, Chang KW, Lin SC*. miR-31 is upregulated in oral premalignant epithelium and contributes to the immortalization of normal oral keratinocytes. Carcinogenesis. 2014;35(5):1162-1171.