副教授 - 陳恆理
服務單位 |
服務部門 |
職稱 |
|---|---|---|
國立陽明交通大學 |
牙醫學系 |
副教授 |
台北榮總 |
牙科部牙周病科 |
總醫師 |
國立陽明交通大學 |
牙醫學系 |
助理教授 |
台北榮總 |
牙科部 |
臨床研究員 |
計畫執行年限 |
計畫名稱 |
計畫補助單位 |
計畫擔任工作 |
|---|---|---|---|
2018/08-2019/07 |
植體表面去毒性模型及骨再整合之體外研究 |
科技部 |
主持人 |
2017/08-2018/10 |
應用人類防禦素以處理植體周圍炎相關之植體細菌汙染 |
科技部 |
主持人 |
2016/08-2017/07 |
長期低氧培養對人類牙周韌帶幹細胞的影響 |
科技部 |
主持人 |
2014/01- 2014/12 |
探討防禦素對人類骨髓幹細胞的影響 |
慶齡基金會 |
主持人 |
2013/09- 2013/12 |
應用防禦素治療骨及牙周組織細菌感染之先期研究 |
國立陽明大學 |
主持人 |
2012/08-2013/07 |
應用防禦素抗菌基因療法於感染骨及牙周缺損之再生治療 |
國科會 |
主持人 |
2012/01- 2012/12 |
應用防禦素基因治療於細菌感染骨缺損治療 |
台北榮總 |
共同主持人 |
2011/09- 2011/12 |
人類beta-defensin 2 抗菌基因治療於骨工程之應用 |
國立陽明大學 |
主持人 |
2010/01- 2010/12 |
應用防禦素基因治療於細菌感染骨再生之前期研究 |
台北榮總 |
共同主持人 |
2009/01-2009/12 |
應用組織工程及基因治療組合技術於齒槽嵴增高術 |
台北榮總 |
共同主持人 |
2008/01-2008/12 |
擴增齒槽骨脊之前期研究- 建立狗骨髓間葉幹細胞培養及慢病毒基因治療系統 |
台北榮總 |
共同主持人 |
2007/08-2008/07 |
骨內給予骨成形蛋白四對人工植牙的影響 |
國科會 |
主持人 |
2007/01-2007/12 |
以組織工程重建齒槽骨脊之前期研究 |
台北榮總 |
共同主持人 |
2004/01-2008/12 |
應用副甲狀腺素之骨再生研究 |
國家衛生院 |
主持人 |
期刊論文（*通訊作者，＃共同作者）
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K.H. Chien, Y.L. Chang, M.L. Wang, J H. Chuang, Y.C. Yang, M.C. Tai, C.Y. Wang, Y.Y. Liu, H.Y. Li, J.T. Chen, S.Y. Kao, H.L. Chen, W.L. Lo*. Promoting induced pluripotent stem cell-driven biomineralization and periodontal regeneration in rats with maxillary-molar defects using injectable BMP-6 hydrogel. Scientific Reports. 2018; 8(1):114.
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P.H. Lee, T.L. Yew, Y.L. Lai, S.Y. Lee, H.L Chen*. Parathyroid hormone gene-activated matrix with DFDBA/collagen composite matrix enhances bone regeneration in rat calvarial bone defects. Journal of the Chinese Medical Association. 2018; 81(8):699-707
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P.H. Lee, M.Y. Chen, Y.L. Lai, S.Y. Lee, and H.L. Chen*. Human beta-defensin-2 and -3 mitigate the negative effects of bacterial contamination on bone healing in rat calvarial defect. Tissue Engineering Part A. 2018; 24(7-8):653-61.
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W.H. Huang, H.L. Chen, P.H. Huang, T.L. Yew, M.W. Lin, S.J. Lin, S.C. Hung*. Hypoxic mesenchymal stem cells engraft and ameliorate limb ischaemia in allogeneic recipients. Cardiovascular Research. 2014; 101(2):266-76.
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Y. Chien, Y.W. Liao, D.M. Liu, H.L. Lin, S.J. Chen, H.L. Chen, C.H. Peng, C.M. Liang, C.Y. Mou, S.H. Chiou*. Corneal repair by human corneal keratocyte-reprogrammed iPSCs and amphiphatic carboxymethyl-hexanoyl chitosan hydrogel. Biomaterials. 2012; 33(32):8003-16.
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H.M. Chang, Y.W. Liao, C.H. Chiang, Y.J. Chen, Y.H. Lai, Y.L. Chang, H.L. Chen, S.Y. Jeng, J.H. Hsieh, C.H. Peng, H.Y. Li, Y. Chien*, S.Y. Chen, L.K. Chen, T.I. Huo*. Improvement of carbon tetrachloride-induced acute hepatic failure by transplantation of induced pluripotent stem cells without reprogramming factor c-Myc. International Journal of Molecular Sciences. 2012; 13(3):3598-617.
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Y.L. Lai, N.J. Kuo, W.K. Hsiao, T.L. Yew, S.Y. Lee, H.L. Chen*. Intramarrow bone morphogenetic protein 4 gene delivery enhances early implant stability in femurs of ovariectomized rabbits. Journal of Periodontology 2011; 82(7):1043-50.
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T.L. Yew, F.Y. Chiu, C.C. Tsai, H.L. Chen, W.P. Lee, Y.J. Chen, M.C. Chang, S.C. Hung*. Knockdown of p21(Cip1/Waf1) enhances proliferation, the expression of stemness markers, and osteogenic potential in human mesenchymal stem cells. Aging Cell 2011; 21(2):349-61.
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T.L. Yew, Y.T. Hung, H.Y. Li, H.W. Chen, L.L. Chen, K.S. Tsai, S.H. Chiou, K.C. Chao, H.L. Chen*, T.F. Huang, S.C. Hung*. Enhancement of wound healing by human multipotent stromal cell conditioned medium: the paracrine factors and p38MAPK activation. Cell Transplantation 2011;20(5):693-706.
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W.K. Hsiao, T.L. Yew, Y.L. Lai, S.Y. Lee, and H.L. Chen*. Intramarrow BMP4 gene delivery improves local bone quality in femurs of ovariectomized rabbits. Journal of Periodontology 2011; 82(6):854-62.
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Y.L. Lai, H.L. Chen, L.Y. Chang, S.Y. Lee*. Resubmergence technique for the management of soft tissue recession around an Implant: Case report. International Journal of Oral & Maxillofacial Implants 2010; 25(1):201-4.
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D.C. Chen, Y.L. Lai, S.Y. Lee, S.L. Huang and H.L. Chen*. Osteoblastic response to collagen scaffolds varied in freezing temperature and glutaraldehyde crosslinking. Journal of Biomedical Materials Research Part A 2007; 80(2):399-409.
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Y.L. Lai, I.C. Chou, Y.C. Liaw, H.L. Chen, Y.C. Lin and S.Y. Lee*. Triple immediate therapy (ridge expansion, soft-tissue augmentation, and provisional restoration) of maxillary anterior single implant: A case report. Journal of Periodontology 2007; 78(7):1348-53.
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H.L. Chen, E.P. Frankenburg, S.A. Goldstein, L.K. McCauley*. The combination of local and systemic parathyroid hormone enhances bone regeneration. Clinical Orthopaedics and Related Research 2003; 416:291-302.
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D.C. Chen, Y.L. Lai, H.L. Chen, S.Y. Lee*. Effect of circumferential undercut placement in the root canal wall on the retention of a tapered post in large and small root canals. Journal of Dentistry 2003; 31(4):247-52.
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H. Chen, B. Demiralp, A. Schneider, A.J. Koh, C. Silve, C.Y. Wang, L.K. McCauley*. Parathyroid hormone and parathyroid hormone related protein exert both pro- and anti-apoptotic effects in mesenchymal cells. Journal of Biological Chemistry 2002; 277(22):19374-81.
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H. Chen, L.K. McCauley, N.J. D’Silva*. cAMP binding protein assay for widespread use in cell signaling studies. Biotechniques 2002;33(1):66-72.
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B. Demiralp, H. Chen, A.J. Koh, E.T. Keller, L.K. McCauley*. Anabolic actions of parathyroid hormone during bone growth are dependent on c-fos. Endocrinology 2002; 143(10):4038-47.
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L.K. McCauley, A.J. Koh-Paige, H. Chen, C. Chen, C. Ontiveros, R. Irwin, L.R. McCabe*: Parathyroid hormone stimulates fra-2 expression in osteoblastic cells in vitro and in vivo. Endocrinology 2001; 142(5):1975-81.