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助理教授 - 洪佩詩

【基本資料】

姓名：洪佩詩 (HUNG, PEI-SHIH)
聯絡電話：(03)932-5192分機3218
電子郵件：g39017005@gmail.com
研究領域：腫瘤生物學，分子生物學
學歷：博士 – 國立陽明大學口腔生物研究所
            學士 – 國立中興大學食品科學系

【經歷】

服務單位
職稱
  • 國立陽明大學附設醫院教學研究所
研究員
  • 國立陽明大學口腔生物研究所
博士後研究員

【榮譽成就】

得獎年度
頒獎單位
獎項名稱
2008
國立陽明大學
研究生優秀論文獎助」甲等論文獎助
2008
中華民國第23屆生物醫學聯合學術年會
優良看板論文壁報獎
2006
國立陽明大學94學年度
學術論文研討會榮獲「臨床醫學與公共衛生研究組」優等獎

【實驗室研究方向】

The expression and functions of miRNAs in oral, gastric and breast cancer.

【研究計畫】

計畫執行年限
計畫名稱
2015/01-2014/12
National Yang-Ming University Hospital, The miRNAs which could contributes to paclitaxel resistance of breast cancer cells, RD2015-033.
2014/01-2014/12
National Yang-Ming University Hospital, The regulation mechanisms of stomatin in breast cancer, RD2014-033.

【發表著作】

期刊論文（*通訊作者，＃共同作者）
  1. Liu CJ, Tsai MM, Hung PS, Kao-SY, Liu TY, Wu KJ, Chiou SH, Lin SC*, Chang KW*. miRNA-31 ablates expression of the HIF regulatory factor FIH to activate the HIF pathway in head and neck carcinoma. Cancer Research 2010; 15;70(4):1635-1644
  2. Lin SC, Liu CJ, Lin JA, Chiang WF, Hung PS, Chang KW*. miRNA-24 up-regulation in oral carcinoma: positive association from clinical and in vitro analysis. Oral Oncology 2010; 46(3):204-208.
  3. Hung PS#, Chen FC#, Kuang SH, Kao SY, Lin SC*, Chang KW*. miRNA-146a induces differentiation of periodontal ligament cells. Journal of Dental Research 2010; 89(3):252-257.
  4. Chang KW#, Hung PS#, Lin IY, Hou CP, Chen LK, Tsai YM, Lin SC*. Curcumin upregulates insulin-like growth factor binding protein-5 (IGFBP-5) and C/EBPα during oral cancer suppression. International Journal of Cancer 2010; 127(1):9-20.
  5. Yang CC#, Hung PS#, Wang PW, Liu CJ, Chu TH, Cheng HW, Lin SC*.  miRNA-181 as a putative biomarker for lymph-node metastasis of oral squamous cell carcinoma. Journal of Oral Pathology & Medicine 2011; 40: 397-404.
  6. Chiang WF#, Hung PS#, Liu SY, Yuan TC, Chang KW, Chen YP, Liu YC, Lin SC*. Increase of ZASC1 gene copy number in recurrent oral carcinoma. Oral Diseases 2011; 17:53-59.
  7. Lo SS*, Hung PS, Chen JH, Tu HF, Fang WL, Chen CY, Chen WT, Gong NR, Wu CW. Overexpression of miRNA-370 and downregulation of its novel target TGFβ-RII contribute to the progression of gastric carcinoma. Oncogene 2102; 31(2):226-237.
  8. Hung PS#, Chang KW#, Kao SY, Chu TH, Liu CJ, Lin SC*. Association between the re2910164 polymorphism in pre-miRNA-146a and oral carcinoma progression. Oral Oncology 2012; 48(5):404-408.
  9. Wang MC#, Hung PS#, Tu HF, Shih WY, Li WC, Chang KW. Lipopolysaccharide induces the migration of human dental pulp cells by up-regulating miRNA-146a. Journal of Endodontics 2012;38(12):1598-1603.
  10. Hung PS#, Liu CJ#, Chou CS, Kao SY, Yang CC, Chang KW, Chiu TH, Lin SC*. miR-146a enhances the oncogenicity of oral carcinoma by concomitant targeting of the IRAK1, TRAF6 and NUMB genes. PLOS One 2013; 26;8(11):e79926.
  11. Hung PS#, Tu HF#, Kao SY, Yang CC, Liu CJ, Huang TY, Chang KW, Lin SC*. miR-31 is upregulated in oral premalignant epithelium and contributes to the immortalization of normal oral keratinocytes. Carcinogenesis. 2014;35(5):1162-1171.
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