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劉崇基1

教授 - 劉崇基

【基本資料】

姓名：劉崇基 (LIU, CHUNG-JI)
電子郵件：cjliu@ms2.mmh.org.tw
研究領域：口腔顎面外科
學歷：碩士 – 陽明大學牙醫學系
            學士 – 陽明大學牙醫學系 

【經歷】

服務單位
職稱
馬偕紀念醫院口腔醫學部
部主任
國立陽明大學
教授
馬偕醫院口腔顎面外科
資深主治醫師
衛生福利部口腔顎面外科
專科醫師
中華民國口腔顎面外科醫學會
常務理事
中華民國口腔顎面外科醫學會
秘書長
中華民國口腔顎面外科醫學會
理事
台北榮民總醫院口腔顎面外科
兼任主治醫師
台北榮民總醫院口腔顎面外科
住院醫師

【研究計畫】

計畫執行年限
計畫名稱
計畫補助單位
計畫擔任工作
2010/08-2013/07
口腔癌癌化過程微RNA 134 及 196 基因表現與功能變化之研究(99-2628-B-195-002-MY3)
國科會
主持人
2010/08- 2013/07
致癌性微型RNA及其標靶基因調節口腔上皮細胞功能及癌化之探討(99-2628-B-010-013-MY3)
國科會
共同主持人
2010/08-2013/07
檳榔萃取物調控微型RNA於口腔癌化之的功能探討(99-2628-B-010-012-MY3)
國科會
共同主持人
2008/08-2011/07
MKP4於口腔癌化角色之功能性探討(97-2314-B-010-027-MY3)
國科會
共同主持人
2007/08-2010/07
miR181微RNA家族成員於口腔癌生成與轉移之功能性探討(96-2628-B-010-033-MY3)
國科會
共同主持人
2007/08-2010/07
位於染色體3q26-27之新穎鋅指致癌蛋白 ZASC1於口腔癌化角色之探討(96-2628-B-010-010-MY3)
國科會
共同主持人
2007/08-2010/07
探討microRNA 31及 211之不同功能性表現在口腔癌癌化過程扮演之角色(96-2314-B-195-018-MY3)
國科會
主持人
2006/08-2007/07
p53及MDM2 基因多型性與口腔鱗狀上皮癌關聯性之研究(95-2314-B-195-013-)
國科會
主持人
2006/08-2007/07
於口腔上皮細胞癌針對EGF受器及NF-κB訊息路徑之基因註解及臨床前期標靶治療(95-2314-B-010-045-MY2)
國科會
共同主持人
2005/08-2006/07
NF-κB 基因多型性與表現於口腔鱗狀上皮癌感受性與進行之研究(94-2314-B-195-015-)
國科會
主持人

【發表著作】

期刊論文（*通訊作者，＃共同作者）
  1. miR-24 up-regulation in oral carcinoma: positive association from clinical and in vitro analysis.Lin SC, Liu CJ, Lin JA, Chiang WF, Hung PS, Chang KW.Oral Oncol. 2010 Mar;46(3):204-8. Epub 2010 Feb 6.
  2. Association between the polymorphisms in exon 12 of hypoxia-inducible factor-1alpha and the clinicopathological features of oral squamous cell carcinoma.Shieh TM, Chang KW, Tu HF, Shih YH, Ko SY, Chen YC, Liu CJ*.Oral Oncol. 2010 Sep;46(9):e47-53. Epub 2010 Jul 24.
  3. Increase of microRNA miR-31 level in plasma could be apotential marker of oral cancer Oral Dis. 2010 May;16(4):360-4. Epub 2010 Mar 9.C-J Liu, S-Y Kao, H-F Tu, M-M Tsai, K-W Chang, S-C Lin
  4. Presurgical serum levels of matrix metalloproteinase-9 and vascular endothelial growth factor in oral squamous cell carcinoma. Liu CJ*, Chang KW, Lin SC, Cheng HW. Oral Oncol. 2009 Oct;45(10):920-5. Epub 2009 Jun 6.
  5. Nuclear STK15 expression is associated with aggressive behaviour of oral carcinoma cells in vivo and in vitro.Kao SY, Chen YP, Tu HF, Liu CJ, Yu AH, Wu CH, Chang KW.J Pathol. 2010 Sep;222(1):99-109.
  6. Identification of increased NBS1 expression as a prognostic marker of squamous cell carcinoma of the oral cavity.Hsu DS, Chang SY, Liu CJ, Tzeng CH, Wu KJ, Kao JY, Yang MH.Cancer Sci. 2010 Apr;101(4):1029-37. Epub 2009 Dec 15.
  7. Areca-treated Fibroblasts Enhance Tumorigenesisof Oral Epithelial CellsH.-H. Lu, C.-J. Liu, T.-Y. Liu,S.-Y. Kao, S.-C. Lin,and K.-W. Chang J Dent Res  87(11):1069-1074, 2008
  8. Direct regulation of TWIST by HIF-1α promotesMetastasis Muh-Hwa Yang, Min-Zu Wu, Shih-Hwa Chiou, Po-Min Chen, Shyue-Yih Chang, Chung-Ji Liu, Shu-Chun Teng and Kou-Juey Wu Nature cell biology 10:3 295-305
  9. IFN-Induced Protein with Tetratricopeptide Repeats 2 Inhibits Migration Activity and Increases Survival of Oral Squamous Cell CarcinomaKuo-Chu Lai, Kuo-Wei Chang, Chung-Ji Liu, Shou-Yen Kao and Te-Chang Lee  Mol Cancer Res. 2008 Sep;6(9):1431-9.
  10. Association between lysyl oxidase polymorphisms and oralsubmucous fibrosis in older male areca chewers Tzong-Ming Shieh, His-Feng Tu, Ti-Hsuan Ku, Shu-Shin Chang, Kuo-Wei Chang, Chung-Ji Liu* J Oral Pathol Med (2009) 38: 109–113
  11. Association between lysyl oxidase polymorphisms and oralsubmucous fibrosis in older male areca chewers Tzong-Ming Shieh, His-Feng Tu, Ti-Hsuan Ku, Shu-Shin Chang, Kuo-Wei Chang, Chung-Ji Liu* J Oral Pathol Med (2009) 38: 109–113
  12. Association between High miR-211 microRNA Expression and the Poor Prognosis of Oral CarcinomaK.-W. Chang, C.-J. Liu, T.-H. Chu,H.-W. Cheng, P.-S. Hung, W.-Y. Hu and S.-C. Lin J Dent Res 87(11):1063-1068, 2008
  13. Positive Correlations of Oct-4 and Nanog in Oral Cancer Stem-Like Cells and High-Grade Oral Squamous Cell Carcinoma Shih-Hwa Chiou, Cheng-ChiaYu,Chi-Yang Huang, Shu-Chun Lin,Chung-Ji Liu, Tung-HuTsai, Shiu-Huey Chou, Chian-Shiu Chien, Hung-Hai Ku, andJeng-Fan Lo Clin Cancer Res 4085 2008;14(13)4085-95
  14. Radial forearm versus anterolateral thigh flap reconstruction after hemiglossectomy: functional assessment of swallowing and speech. Hsiao HT, Leu YS, Liu CJ, Tung KY, Lin CC.J Reconstr Microsurg. 2008 Feb;24(2):85-8.
  15. Vascular endothelial growth factor 936 C/T polymorphism is associated with vascular invasion in oral squamous cell carcinoma. Cheng CY, Chang CS, Liu CJ*, Kao SY. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Jul;106(1):79-84
  16. Differential gene expression signature between primary and metastatic head and neck squamous cell carcinoma.Liu CJ, Liu TY, Kuo LT, Cheng HW, Chu TH, Chang KW, Lin SC. J Pathol. 2008 Mar;214(4):489-97.
  17. Insulin-like growth factor binding protein-5 (IGFBP-5) suppresses the tumourigenesis of head and neck squamous cell carcinoma.Hung PS, Kao SY, Shih YH, Chiou SH, Liu CJ, Chang KW, Lin SC.J Pathol. 2008 Feb;214(3):368-76.
  18. Interaction between HSP60 and b-catenin promotes metastasisYa-Ping Tsai, Muh-Hwa Yang, Chi-Hung Huang, Shyue-Yih Chang, Po-Min Chen, Chung-Ji Liu, Shu- Chun Teng and Kou-Juey Wu_Carcinogenesis vol.30 no.6 pp.1049–1057, 2009
  19. Increase of MMP-13 expression in multi-stage oralcarcinogenesis and epigallocatechin-3-gallate suppress MMP-13 expressionW-C Chiang, Y-K Wong, S-C Lin, K-W Chang, C-J Liu* Oral Diseases (2006) 12, 27–33.
  20. Functional polymorphism in NFKB1 promoter is related to the risksof oral squamous cell carcinoma occurring on older male areca(betel) chewersShu-Chun Lin , Chung-Ji Liu , Wen-I Yeh, Man-Tin Lui , Kuo-Wei Chang  Che-Shoa Chang , Cancer Letters 243 (2006) 47–54
  21. Increase of disintergin metalloprotease 10 (ADAM10) expressionin oral squamous cell carcinomaShun-Yao Ko, Shu-Chun Lin, Yong-Kie Wong, Chung-Ji Liu ,Kuo-Wei Chang  Tsung-Yun Liu Cancer Letters  244 (2006) 1–11
  22. MICA and MICB overexpression in oral squamous cell carcinomaChung-Ji Liu, Man-Tin Lui, Hsin-Lan Chen, Shu-Chun Lin, Kuo-Wei Chang J Oral Pathol Med (2007) 36: 43–7
  23. Neck Abscess and Necrotizing Fasciitis Caused by Salmonella Infection: Chin-Wan Luo  Chung-Ji Liu*, Oral Maxillofac Surg65:1032-1034, 2007
  24. Association of pretreatment thrombocytosis with disease progression and survival in oral squamous cell carcinoma Chia Chun Lu , Kuo Wei Changb, Feng Chih Chou, Chieh Yuan Cheng, Chung Ji Liu* Oral Oncology (2007) 43, 283– 288
  25. Human papillomaviruses in oral squamous cell carcinoma andpre-cancerous lesions detected by PCR-based gene-chip arrayC.-W. Luo, C.-H. Roan,C.-J. Liu*, Int. J. Oral Maxillofac. Surg. 2007; 36: 153–158
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